Doctoral candidates of Doctoral Programme Brain & Mind and other interested doctoral candidates and late-stage MSc students. Optional course.
Basic neuroscience and genetic courses.
After the course, the students will:
- understand the basic principles of gene regulation by epigenetic mechanisms
- be familiar with the traditional and also cutting edge methods of evaluation of epigenetic changes
- understand epigenetic modulation of plasticity and development of SNC
- comprehend the involvement of epigenetics on brain functions and disorders
The course will be offered every other year, period II.
- Theory and an overview of methodological approaches to study the main epigenetic events: DNA methylation, histone modifications, non-coding RNA.
- review of the most critical neuroepigenetic processes involved in SNC functions and disorders: learning and memory, circadian cycle, Rett syndrome, Prader-Willi/Angelman syndrome; Alzheimer’s disorders, stress-related psychiatry disorders, autism.
This is an intensive course requiring compulsory attendance.
Lectures, small-group discussions and presentations, required literature, written exams (Exam1, Exam2).
- Contact teaching (10h): Lectures and Journal Club presentations (100% participation)
- Independent work (40-50h): reading course material and preparation of the JC presentation.
- Optional exam (2 cr): independent work and exam (30-40h)
Course reading material will be provided by the teacher. Suggested reading of academic books, scientific papers and on-line videos.
The course will be graded as 0-5. Evaluation will be based on written presential examination (ExamI1 and Exam2) and active participation during the journal club which will give up to 50 % of the final grade. A successful Exam1 will exempt the Exam2 evaluation.
Instruction language: English.
Caroline Biojone and Juzoh Umemori