Kaisa_2012_3_photo by Veikko Somerpuro

The course is postponed

The course is postponed to Autumn 2020. More information will follow!!!

Postdocs and others who are not able to register below, may register to dpdr-info@helsinki.fi (pls indicate day/s on which you plan to participate).

The first two sessions (pre-assignments on 5.6. and Day 1 on 11.6.) will be organized through Zoom (link available later)
Day 2 on 17.8. and Day 3 on 18.8. will be organized in Viikki and Meilahti. The exact rooms will be announced later.

Enrol
3.3.2020 at 14:00 - 31.5.2020 at 16:00

Timetable

Here is the course’s teaching schedule. Check the description for possible other schedules.

DateTimeLocation
Thu 11.6.2020
08:00 - 16:00

Material

Description

During this course, we will present state of the art methods on how to study the biology, the function and drug actions in using cellular and in vivo model systems . The overall aim is to increase know-how and understanding of techiques that allow quantitative analysis of drug effects in biological systmes. We will provide examples on how to study drug effects and perform gene manipulations in a physiologically relevant manner. The objective of the course is to demonstrate the state of the the art methodology on how to study biology, function and drug actions in using cellular and in vivo model systems.

The course is intended for master, PhD students and post doctoral researchers interested in biopharmaceutical, pharmacological and neurobiological research. Its focus shifts every year between (i) examples of drug screening and how to develop and validate new reporter systems in vitro and (ii) how to study functions in vivo with emphasis to a certain cell type. This year (2020) we will focus on image analysis and fluorescent and luciferace probes in cell culture and in vivo studies. Special attention will be given on CRISPR/Cas9-based genome editing and potential advances it can bring to drug research. We aim to provide CRISPR tutorial every other year and this is a unique opportunity for students to learn the basics of guide RNA selection and assay design. The course will be given by local and external speakers with high-profile international careers who are who are actively working on these topics.

Examination: Examination will be organized after the course in moodle.

Lectures and moodle examination 3 ECTS

3 ECTS lectures and examination

The objective of the course if provide the state of art knowledge of current methods how to study biology,
function and drug actions in using cellular and in vivo model systems. The course is intended for master and
PhD students interested in biopharmaceutical, pharmacological and neurobiologal research. The course is
taking turns to present every other year examples of drug screening and how to develop and how to validate
new reporter systems in cultures and every other year with a specifc focus on certain cell type i.e. how to
to study functionsin vivo. On of the aims of the course is to provide examples how to study drug effects and
do gene manipulations in physiologically relevant manner. 2019 we will focus on non-neuronal cells in the
brain including astrocytes, microglia, oligodendrocytes and glia precursor cells. The course includes local
and external speakers with high-profile international careers who are who are actively working on these
topics.
The long term goal of the course is to bring expertice on CRISPR/Cas9-based genome editing and knowledge
of the advantages it can bring to drug research. We aim to provide CRISPR tutorial every other year and it
is a unique opportunity for students to learn the basics of guide RNA selection and assay design.

Mikko Airavaara