B.Sc. level basic courses in genetics and genomics (Genetiikan perusteet, Molekyyligenetiikka ja genomiikka).
After the course the student will be able to describe the basic structure and function of the human genome at the chromosome and DNA level, and be able to identify different types of DNA and chromosome aberrations and their association with genetic disease, including cancer.
Period 1, third year (B.Sc) or later (M.Sc.), arranged every year.
The following topics are covered:
- The organization and function of the human genome,
- Principles of genetic variation,
- Single-gene disorders: inheritance patterns, phenotype variability and allele frequencies,
- Abnormal epigenetic regulation in mendelian disorders and uniparental disomy,
- Genetic variation producing disease-causing abnormalities in DNA and chromosomes,
- Identifying disease genes and genetic susceptibility to complex disease,
- Genetic approaches to treating disease,
- Cancer genetics and genomics,
- Epigenetic dysregulation in cancer,
- Genetic testing, ethical questions and genetic counselling
Basis for grade: exam , and successful completion of exercises in Moodle
The course includes 28 hours of lectures, exercises in Moodle, an exam, and 105 hours of independent work (including exercises in Moodle).
Strachan T, Goodship J & Chinnery P: Genetics and Genomics in Medicine, Garland Science (latest edition), lecture material.
Grading is on the scale 0-5, based on the exam.
All lectures are in English.
University lecturer Katarina Pelin
Replaces the previous courses 52911 Syövän genetiikka, 3 op + 52714 Ihmisgenetiikka, 3 op (together).