Basic knowledge in Genetics and in Microbiology is required.
The student knows the principles for microbial inheritance, diversity and evolution.
The student has quite detailed knowledge of replication, transcription and translation in both prokaryotes (bacteria and archaea) and eukaryotes, and the relevant differences between these kingdoms.
The student can explain regulation of microbial gene expression.
The student knows the physiological and mechanistic differences between prokaryotic and eukaryotic gene expression and regulation of gene expression.
The student has a general view of how microbial genetics has been utilized in genetical engineering and in biotechnology.
Period II, 2019-20, (November 5. – 28.)
Principles of microbial inheritance, diversity and evolution, including the generation of mutants, exchange of genetic material, and recombination as drivers of evolution. Also genetics and role of bacteriophages as well as mobile genetic elements in bacterial evolution and diversity is explained. Attention will be put also on regulation of gene expression and epigenetics. Certain aspects of biotechnology, mainly in nonmedical fields will be taught.
Recommended literature: Brock-Microbiology
The course will have a final exam that stands for 60% of the grade. 40% of the grade will be based on the journal club presentation and discussion.
All lecturing in English. Exam can be taken in English, Suomeksi, på Svenska
Lectures, where presence is recommended but not mandatory, will be 20h (10 x 2h). These lectures will be also available as video broadcasts on the net, where interaction will be made possible. The videos will be recorded and made available later on the net. Two lecture dates will be allocated for presentations by students in the form of journal clubs where students in groups of 2 – 4 (depending on total number) will explain the essence of 2-5 relevant scientific papers dealing with a specific chosen topic. Preparation for the own presentation at journal club estimated at 40h, and preparation for discussions of presentations by other teams, and preparation for final exam additional 70 h.