Kaisa_2012_3_photo by Veikko Somerpuro

25.3.2020 at 00:00 - 14.4.2020 at 23:59


Fri 24.4.2020
16:00 - 20:00


Students of the Master’s Programme in Translational Medicine; students of other Master’s programmes and doctoral programmes. Attendance limited to 30 students.

TMED-909 Human Anatomy and Physiology is required from TRANSMED students
TMED-105 Pathologic Basis of Disease is recommended for TRANSMED students

The student will

-Acquire basic knowledge on the principles of neoplastic growth, cancer progression and dissemination
- Acquire basic understanding on the interplay between different cell types during neoplastic growth
-Acquire knowledge on major research methodologies and disease models in cancer biology

Period III, second study year. The course is arranged annually.

Lectures provide an overview of the following aspects in cancer biology:

  • What cancer is
  • Signal transduction in cancer cells
  • Oncogenes and tumour suppressor genes
  • The tumour microenvironment
  • Cancer metastasis
  • Angiogenesis and lymphangiogenesis
  • Cancer stem cells
  • Transcriptional regulation in cancer
  • Cancer and the immune system
  • Tumour viruses
  • Cancer metabolism
  • Data analysis in cancers
  • Targeted therapies and pharmacogenomics

Basic methods in cancer research

Research articles:

Hanahan and Weinberg: The Hallmarks of Cancer, Cell, pp. 57–70, 2000
Hanahan and Weinberg: Hallmarks of Cancer: The Next Generation. Cell. 144(5):646-74, 2011
Textbook: Weinberg, RA: The Biology of Cancer, 2014

Active discussion during interactive lectures

Grading scale 1–5 (passing grades). Completion requires 75% attendance and a passing grade on the exam. The grading is based on the exam.

Responsible teachers are doc. Pirjo Laakkonen and prof. Päivi Ojala.

This is a lecture course; the attendance requirement is 75% over the entire course.

The course replaces 30387 Cancer Biology, 3.5 cr