Students of the Master’s Programme in Translational Medicine, other Master’s and doctoral students.
The aim of the course is to introduce the terminology, methodology and selected research applications in personalised as well as precision medicine.
After the course, the student will
Be able to describe the terminology and explain the advantages and disadvantages of precision medicine
Be able to compare the different omics and the relevant technologies applied in precision medicine Be aware of what related research is performed in the local campus area and can discuss the topic on a general level
Be able to describe environmental and genetic risk factors affecting health and their individual influence
Period IV. The course is arranged annually.
1. P4 Medicine
• Introduction to personalized medicine (lecture)
• Genome data (lecture)
• Personalized mental health (lecture)
2. Precision Medicine at the Meilahti Campus
• Ovarian cancer (lecture)
• Haematological malignancies (lecture)
• Urological malignancies (lecture)
• Group assignment
3. Omics and Technologies (demos)
• Different omics and technologies enabling precision medicine (lecture)
• FIMM-HTB: Drug sensitivity and resistance testing (wet-lab visit to robotics laboratory)
• Tissue diagnostics & Webmicroscope (demo)
• Biobank visit (demo)
4. Applications of P4 medicine – current studies in cardiovascular diseases and genomics
• Metabolomics technologies enabling precision medicine-with a focus on cardiovascular diseases
• Utilizing genome data in drug development
5. Applications of P4 medicine – current studies in wellness studies and my data.
• Wellness studies ja Digital Health Revolution
• The Biobank, data, and ethical legislation (lecture)
• Artificial intelligence for medical diagnostics
6. Group work
Lecture slides and supportive reading will be distributed via the Moodle learning environment.
Lectures, demonstrations, group work and feedback discussions.
Grading 1-5. For completion, 85% of attendance in the lectures and a passing grade on the exam are required.
Responsible teacher: Nina Linder, senior researcher
5 cr: TMED-910A Genome profiling and TMED-910C Personalized medicine are compulsory.
6 cr: Select also TMED-910B NG sequencing. TMED-910B NG Sequencing has limited capacity (10 students) and accepts primarily TRANSMED students.
The course consists of contact teaching and lectures, and individual learning requires the students to read supporting material for each course lecture as well as engage in team-based learning in preparing for the group presentations. Distance learning is not possible.
Pre-assignment 4 h
Contact teaching/lectures 6 x 3 h = 18 h
Group assignments 10 h
Independent studies 32 h
Feedback 1 h
Exam 2 h
Prerequisites: Basic familiarity with molecular biology concepts is expected.